What to Expect During Your First Month of MAT

Beginning medication-assisted treatment (MAT) is more than filling a prescription. It’s a commitment to yourself and to your future. At Jasper Grove Recovery in Indianapolis, we understand that this step can bring a mix of emotions. You may feel nervous about starting medication or uncertain about what daily life will look like. You may also feel ready, determined, and hopeful. All of those feelings are normal. 

Our job is to walk with you through every stage of your first month. We provide medical guidance, emotional support, and the reassurance that comes from knowing you are not doing this alone. With that in mind, here’s what you can expect during your first 30 days of MAT. 

First 30 days at a glance: MAT timeline, goals, and what “stabilization” really means 

Your first month of MAT is structured to promote safety, comfort, and progress. This period is all about bringing stability to your body and mind, giving you the foundation for meaningful recovery. Here’s a quick overview of what you’ll experience in these critical first 30 days: 

  • Days 0–3: Induction – Careful evaluation, starting medication, managing withdrawal 
  • Days 4–14: Early stabilization – Dose adjustments, craving control, side-effect management, and starting therapy 
  • Days 15–30: Stabilization to maintenance – Increased functioning, routine development, and deeper engagement in counseling 

Throughout the process, our team checks in regularly, makes adjustments when needed, and ensures that your care feels steady and predictable. 

Induction → stabilization → maintenance: The standard MAT timeline and milestones 

MAT at Jasper Grove follows a well-structured approach grounded in evidence-based protocols. 

Induction (Days 0–3)

The first stage begins with a comprehensive assessment. We review your medical history, run lab tests, and learn about your substance use and mental health background. Once we have a clear picture, we introduce medication at the right time and dose. 

This period often overlaps with early withdrawal, which can be uncomfortable. To ease the process, our staff monitors you closely, sometimes checking in daily. The goal is to minimize discomfort while giving your body its first taste of balance.

Early stabilization (Days 4–14)

As your body adjusts, we pay close attention to how you’re responding to the medication. This period involves gradual dose adjustments to ease cravings and minimize side effects. Here, you’ll meet our counseling team, receive psychoeducation about addiction and recovery, and begin participating in individual or group therapy.

Stabilization to maintenance (Days 15–30)

By the third stage, you should feel noticeable progress. Cravings decrease. Withdrawal symptoms fade. Sleep improves, and your energy levels begin to return. With greater stability, you’ll start establishing daily routines and focusing on therapy in a deeper way. 

This is often the point when confidence grows. For many, it’s the first time in a long time that life feels manageable again. Therapy sessions help you explore triggers, strengthen coping skills, and practice relapse prevention strategies. Some patients may also begin family counseling during this time to repair relationships and improve communication. 

Week-by-week MAT timeline: What to expect in your first month 

Week 1 

  • Medical evaluation, lab testing, and mental health screening. 
  • Start of medication such as buprenorphine, naltrexone, or methadone. 
  • The primary goal is to reduce withdrawal and stabilize brain chemistry. 
  • You may still feel lingering symptoms, but they are often milder. Daily check-ins with the care team help keep you comfortable.

Week 2 

  • Frequent follow-ups ensure your medication is effective. 
  • Individual counseling sessions begin, with introductions to group therapy. 
  • Side effects are addressed quickly if they occur. 
  • Most patients notice better sleep, steadier moods, and the ability to focus more clearly. 

Weeks 3–4 

  • Medication dose becomes consistent, and cravings are significantly reduced. 
  • Daily structure improves, giving you more stability at work, school, or home. 
  • Therapy sessions go deeper, focusing on relapse prevention and long-term strategies. 
  • You may notice stronger relationships, more consistent energy, and a renewed sense of hope. 

MAT therapy benefits and session expectations 

MAT is most effective when paired with counseling and supportive services. Here’s what you can expect from therapy at Jasper Grove Recovery: 

  • Individual therapy: You’ll work with a licensed therapist to identify triggers, challenge harmful beliefs, address trauma, and create personalized coping skills.
  • Group therapy: In a safe, respectful space, you’ll share successes and challenges, learn from others’ stories, and build accountability within a supportive peer community.
  • Family therapy: When appropriate, our clinical team invites loved ones to participate in rebuilding trust, improving communication, and understanding the MAT process. 

Session expectations 

  • Sessions may occur several times weekly, especially early on. 
  • Therapists use evidence-based methods like cognitive-behavioral therapy (CBT), relapse prevention techniques, and motivational interviewing. 
  • You’ll have opportunities to set practical recovery goals, develop new routines, and gain education about addiction and the brain. 

Overcoming challenges: Your questions answered 

No. The medications used in MAT are prescribed at safe, therapeutic doses. They do not create a high. Instead, they reduce cravings and withdrawal, giving you a stronger foundation for recovery. 

There isn’t a single answer. Some patients benefit from MAT for months, others for years. Your care team reviews your progress regularly and works with you to decide what’s best.

Mild side effects are common at the beginning but often fade as your body adjusts. If discomfort continues, our team can make adjustments to improve your experience. 

For many patients, MAT makes it easier to work, maintain relationships, and focus on responsibilities. The goal is to restore normal function so you can move forward with your life. 

Building a foundation for recovery 

We know that long-term recovery is about much more than just medications—it’s about relationships, structure, hope, and practical support. During your first 30 days, you’ll work not only with your treatment team but also with peers, family, and our extended recovery network. 

  • Daily/weekly schedules: Expect a structured routine that balances medical appointments, therapy, nutrition, rest, and peer support.
  • Life skills and education: You’ll receive education on managing triggers, setting healthy boundaries, and planning for employment or education if needed.
  • Alumni and aftercare: We help you create a concrete plan for after your first month, including outpatient therapy, ongoing support groups, and connection to community resources.

Real expertise. Real care. 

At Jasper Grove Recovery, you are met with both medical expertise and genuine compassion. Every appointment, therapy session, and check-in is designed to protect your dignity while moving you toward stability. By the end of your first month, you’ll have a foundation of care and support that helps make long-term recovery possible. 

Begin your path forward 

Starting MAT is a sign of strength and hope. The first month may bring challenges, but you will not face them alone. At Jasper Grove Recovery, you’ll find a team that understands the process, cares about your progress, and is committed to helping you succeed. 

If you’re ready to begin, reach out today at 317.527.4529. Your future is waiting, and we’re here to walk beside you as you take the first step.